Lonny Gold is originally from Canada. His first contact with the method goes back to a trip to Ottawa, in Canada, in 1978. It started with the Canadian government who was using it, especially to teach French to English speaking civil servants. Lonny Gold began to become more familiar with it in Paris, thanks to a woman called V. Saferis, who brought it from Bulgaria to the West.

In this work, the theme “ways of using modern technologies in the technical training of qualified athletes” is widely covered. Historical features of physical education and sports development on the basis of modern approaches in the lectures methods of increasing the effectiveness of training and control questions have been developed. In the summary section, recommendations for the application of pedagogical technology in teaching of teaching are given.

The main function of connective tissues is to provide structural support to other tissues. Cartilage and bone are the main connective tissue types, other types are areolar connective tissue, which holds organs together, and dense connective tissue, which forms ligaments and tendons. We studied 47 pregnant women with uBD and 15 healthy pregnant women without uBD aged 24 to 30 years. 50% of women with uBD were at risk of abortion, and the risk of preterm birth was observed 6 times more often than in healthy pregnant women. Thus, pregnant women with signs of various forms of uBD belong to high-risk groups for obstetric and perinatal pathology and therefore need to be closely monitored during pregnancy, childbirth and the postpartum period. In addition, newborns who have a high probability of inheriting this disease must be examined.

The article provides up-to-date data on the etiology, etiology, clinical picture and problems with the treatment of generalized periodontitis. The authors came to the conclusion that the treatment should be comprehensive and aimed at eliminating inflammation in the periodontal area, eliminating periodontal pockets, stimulating restorative bone formation, restoring function and adversely affecting the general health and quality of life of the patient. The use of conductors in the drug for the treatment of inflammatory and destructive periodontal diseases is due to the ability to increase the permeability conductivity of the drug to the inflammatory focus, allowing to create an effective concentration of the active drug component, which is part of the composition in the entire volume of periodontal lesions, maintaining it throughout the entire period of treatment.

Social security contributions play a vital role in the provision of pensions, serving as a cornerstone of retirement income for millions of individuals worldwide. The significance of social security contributions in pension provision cannot be overstated, as they provide a safety net for workers, ensuring that they are financially secure in their golden years. This article will delve into the role of social security contributions in pension provision, examining their importance, benefits, and challenges, as well as exploring potential reforms to strengthen their efficacy.

Investments are one of the main factors of ensuring economic growth and economic development. In recent years, the investment processes have been activated in Uzbekistan. As we know, attracting investments is one of the main goals of every country. Investments have a great role in achieving sustainable economic growth, implementing structural changes in the economy, and improving the living standards of the population.

A favorable investment environment for investors has been established in our country today, and this convenience is bearing fruit. attracting investors, on the one hand, provides new technologies, management experience, knowledge and stable economic growth in the country, on the other hand, it strengthens the global economic opportunities due to the integration of the rich resources and production capabilities of the republic into the world economy. In particular, the 26th goal of the new development strategy of Uzbekistan for 2022-2026, approved by President Sh.M. Mirziyoyev, is named as follows: "To further improve the investment environment in the country and increase its attractiveness, in the next five years 120 billion US dollars, including 70 to take measures to attract foreign investments of billion dollars".

The "Uzbek Sign Language Classifier Based on Machine Learning" presents a groundbreaking approach to enhancing communication accessibility for the deaf and hard-of-hearing community in Uzbekistan. This research focuses on developing a robust machine learning model to recognize and classify Uzbek Sign Language (UzSL) signs, enabling real-time translation and fostering better integration of sign language users into various aspects of society. Utilizing advanced deep learning techniques, particularly Convolutional Neural Networks (CNNs) and Recurrent Neural Networks (RNNs), this study addresses the intricate challenges associated with sign language recognition, such as gesture segmentation, feature extraction, and accurate classification. The dataset for this project comprises a comprehensive collection of images and videos of Uzbek sign language gestures. These data points undergo meticulous preprocessing, including normalization and augmentation, to enhance model training. The proposed model architecture leverages CNNs for spatial feature extraction and RNNs for capturing temporal dependencies, ensuring high accuracy in recognizing dynamic sign sequences. Additionally, the integration of transfer learning techniques, employing pre-trained models, significantly improves the model's performance, particularly given the relatively limited size of the dataset. Extensive experimentation and validation are conducted to fine-tune the model's hyper parameters, optimizing its accuracy and robustness. The results demonstrate a promising accuracy rate, highlighting the model's capability to accurately recognize and classify a wide range of Uzbek sign language gestures. Furthermore, this research underscores the importance of developing localized sign language recognition systems, tailored to the specific linguistic and cultural nuances of the target community.

This study investigates the phenomenon of cultivation shock experienced by international students in Indonesia and explores strategies for navigating this transition effectively. Drawing on qualitative data gathered through interviews and surveys, the research delves into the challenges faced by foreign students as they adapt to the cultural, social, and academic landscapes of Indonesia. By examining the factors contributing to cultivation shock and identifying coping mechanisms utilized by students, this paper offers insights into how educational institutions and support systems can better assist international students in their adjustment process.

This article is devoted to the development of scientifically based proposals and recommendations on the continuous monitoring of the state of their agricultural land, the prevention and elimination of identified negative conditions, the preservation and increase of soil fertility, conservation and the effective use of land resources

Prolapse of the female genital organs is observed in women who gave birth through the vaginal birth canal, gave birth to large fetuses, complicated labor, birth canal injuries with genetic factors that are overweight, hysterectomy in history, hormonal disorders, engaged in hard physical labor, suffering from pathologies leading to increased intra-abdominal pressure.

Recently, the main reason for patients to go to the dentist are periodontal diseases, leading to premature formation of blood clots, a decrease in quality of life due to bad breath, bleeding gums and dental hyperesthesia. Based on the study, the results of the treatment of 112 patients examined from 2019 to 2022 in the department of Orthopedic Dentistry of the Samarkand Regional Dental Clinic were analyzed. According to the results of our study, chronic diffuse periodontitis was more often observed in the group of patients aged 30-39 years – in 39 (34.8%) patients. In chronic diffuse periodontitis, a clear clinical effect was obtained when using the Prozone device with a special disposable Perio tip for 18 seconds, which is equivalent to treating periodontal pockets in combination with an ozonated solution of sodium hypochlorite. The index figures were two times lower. Cytobacterioscopic data indicate that the inflammation decreased and was eliminated within a year.

Die Hauptfunktion der Bindegewebe besteht darin, anderen Geweben strukturelle Unterstützung zu bieten. Knorpel und Knochen sind die wichtigsten Bindegewebetypen, andere Typen sind areolares Bindegewebe, das Organe zusammenhält, und dichtes Bindegewebe, das Bänder und Sehnen bildet. Wir untersuchten 47 schwangere Frauen mit uBD und 15 gesunde schwangere Frauen ohne uBD im Alter von 24 bis 30 Jahren. Bei 50 % der Frauen mit uBD bestand die Gefahr eines Schwangerschaftsabbruchs, und die Gefahr einer Frühgeburt wurde 6-mal häufiger beobachtet als bei gesunden schwangeren Frauen. Somit gehören schwangere Frauen mit Anzeichen verschiedener Formen von uBD zu Hochrisikogruppen für geburtshilfliche und perinatale Pathologie und müssen daher während der Schwangerschaft, der Geburt und der postpartalen Phase engmaschig überwacht werden. Außerdem müssen Neugeborene untersucht werden, bei denen eine hohe Wahrscheinlichkeit besteht, diese Krankheit zu erben.

This article examines the prospects for the introduction of Islamic securities in the financial market of Uzbekistan, includes existing problems and potential solutions. With the growing interest in Islamic finance globally, Uzbekistan is going through an important period to diversify its financial products and secure a wider investor base. However, a number of obstacles prevent the smooth integration of Islamic securities, including the absence of a regulatory legal framework, lack of awareness and market infrastructure. This article analyzes the experience of other countries and offers solutions to overcome these difficulties, taking into account the unique socio-economic conditions of Uzbekistan.

The rapid development of technology has not gone unnoticed in the learning process. Although VR (virtual reality) technologies are no longer a new concept, they have only recently begun to be used in education. Therefore, in this article we will talk about the reasons for the use of VR in education, how it will change the future of VR education systems, how to use virtual reality technologies in education today.

Recently, the city of Samarkand has implemented a set of measures aimed at improving, diagnosing and treating vertical anomalies, namely open bite, and at the moment many scientists and practitioners have begun to study more deeply the factors leading to the development of this anomaly. In clinical practice, etiological factors, endogenous and exogenous factors, as well as the living conditions of this patient, taking into account the age of the patient, are of particular importance. We carried out preventive measures for children aged 6 to 15 in 37 patients with an open bite.[1,2]

    Taking into account all aspects of this anomaly, we set ourselves the task of diagnosing patients with open occlusion using modern methods, taking into account their age and type of anomaly.

 open bite is considered as an independent form of dental anomalies, and can be combined with other disorders in the transversal or sagittal direction.[3]

According to the literature, an open bite occurs in 62% of cases together with the mesial ratio of dentition

An open bite is a serious anomaly of the maxillary system. According to the results of a survey and observation by Nigmatova R.N., Shaamukhamedov F.A., Nigmatova I.M. (2017), open bite was 1.4% among children aged 3-6 years. According to L.P. Grigoriev (1995), 1.12% in children aged 7-16 years. 2.7% in the distribution of anomalies of the maxillary system.[5,6].

However, a number of researchers claim that by the age of 9-10, the frequency of open bite decreases, which is associated with the elimination of bad habits that contribute to the development of the anomaly, as well as with the normalization of respiratory and swallowing functions. In later adolescence, there may be a repeated increase in the prevalence of open bite due to late bone growth in the facial region of the skull [4].

The most common causes of complications in the mouth and the unsuitability of fixed structures are considered to be inflammatory processes, caries and its complications (16,4–25,2 %) [7,8,12], thermal burns of the pulp (4.3%) [4,6,9], cementation of the supporting crowns (8-21% of all complications). These processes often develop in the area of the edge of artificial crowns and are caused by the destruction of the cement layer that fixes the non-removable prosthesis. One of the typical complications of dental prosthetics, which often develops within the first year after fixation of the artificial crown, is the exposure of the neck of the tooth root due to gum recession [3,5,11].

This article covers information on innovative technologies for physical development of school-age children.

The treatment of patients with chronic periodontitis is one of the most difficult and important tasks of modern dentistry. 134 patients with endodontic treatment with two of the most common types of pastes were examined on an outpatient basis: resorcinol-formalin and Calcevit. According to the type of paste, all the examined patients were divided into two groups: 78 patients (51.5%) whose teeth were sealed with resorcinol-formalin paste and 56 patients (48.5%) with Calcite paste. According to the results of the study, it was found that in the group of teeth previously treated with resorcinol-formalin paste, more than 2/3 were molars (77.0 + 2.2%), every fifth tooth was premolar (19.1 + 2.0%) and there were fewer front teeth (3.9 + 1.0%). In the group of teeth previously treated with Calcite paste, the ratio of tooth types in different age subgroups differed. Almost equal proportions in frequency were noted for the anterior teeth (29.2 + 2.4%), premolars (29.8 + 2.4%), and the proportion of molars was slightly higher (41.0 + 2.4%).

An important role in the growth of the level of socio-economic development of Regions is played by the income and expenses allocated from the local budget of those regions. The more budget revenues increase, the better the quality of the area's living standards. Therefore, the state regulation of local budget revenues, consideration and implementation of measures to further increase it have become one of the most pressing issues of mamalakat today. It is important to improve the economic and social condition of the regions, increase its income in the rain, regulate the income of the local budget by the state and increase it. That is why strengthening the economic potential of the country, increasing the welfare of living in the hudus, primarily the formation of diverse sources of local budget income, is largely due to the fact that the state regulates income.

The number of cesarean sections around the world is increasing every year. This is influenced by the rapid development of modern medical science, improved surgical techniques, new suture materials and broad-spectrum antibiotics, pain relief, and the change in society's attitude to childbirth. According to the World Health Organization (WHO), cesarean section (CS) is the most widely used operative method of childbirth today. Determining the role of CS practice in the search for ways to reduce perinatal and maternal morbidity and mortality is essential. In some cases, this method of delivery is the only way to reduce maternal mortality: premature separation of the normally located placenta and / or the appearance of signs of its partial separation, severe hypertensive conditions, including a severe degree of preeclampsia and eclampsia, somatic complications that lead to complications in the mother's natural delivery pathologies.

Thus, the tactics of taking women with a scar on the uterus through natural childbirth, with adequate prenatal preparation, the development of criteria for assessing the adjustment of the surgical scar, the lack of special criteria for predicting the probability of natural childbirth in pregnant women who underwent cesarean section, the special urgency of finding a solution to these issues defines. Therefore, it is necessary to study the condition of women with uterine

The article reveals the conceptual foundations and components of gaming technologies. The functions of gaming technologies in foreign language lessons are analyzed, as well as the conditions of their use in the educational process. Examples of games that can be used to develop lexical skills are given.

One of the problems of modern clinical dentistry is the growth of inflammatory diseases of the oral cavity, which occur against the background of secondary immunodeficiency [3, 6, 8]. The internal factor affecting the immune response is the endocrine system, which is part of the complex of neuroclin regulation of homeostasis. An important role in the pathogenesis of various dental diseases is assigned to a complex multifunctional relationship between the immune, nervous and endocrine systems.

One of the important directions of youth policy in Uzbekistan is wide involvement of talented young people in science. Year by year, more favorable conditions and opportunities are created for the comprehensive development of young people. In this article, the content and essence of intellectual ability of students, ways of its development and the problem of development of intellectual abilities of future specialists are interpreted.

This article examines the analysis of the features of the formation of linguacultural competencies of students of the non-philological faculty of a pedagogical university on the basis of a competency-based approach. The leading approaches to the study of this process are: analysis of the concept of linguacultural competence and its main components, analysis of the activities of methodologists and practicing teachers in the formation of linguacultural competence of students at a pedagogical university. based on a competency-based approach.

This is a philosophical and cultural trend, a special mindset. Arose in France in the 1960s, an atmosphere of intellectual resistance to the total offensive of mass culture on human consciousness. In Russia, when Marxism collapsed as an ideology providing a reasonable approach to life, rational explanation went away and the realization of irrationality came. Postmodernism focused on the phenomenon of fragmentation, split in the consciousness of the individual. Postmodernism does not give advice, but describes a state of consciousness. The art of postmodernism is ironic, sarcastic, grotesque (after I.P. Ilyin).

Aims: This study aims to compare the effectiveness of treatment between anti-vascular endothelial growth factor (anti-VEGF) agents in diabetic macular edema (DME) patients with disorganization of retinal inner layers (DRIL). Epiretinal membrane, serous macular detachment, ellipsoid zone (EZ) disorder, external limiting membrane (ELM) disorder, and hyperreflective foci were also examined.

Methods: Patients treated for DME and also had DRIL were included in the study. The study design was retrospective and cross-sectional. The complete ophthalmologic records and imaging were scanned at the beginning, 3rd-month, 6th-month, and 12th-month follow-up, and the treatments administered were recorded. Anti-VEGF agents administered to the patients were examined in three groups: bevacizumab, ranibizumab, and aflibercept.

This article explores the significance of personal accumulative pensions in the broader context of pension provision. It examines various aspects such as their impact on financial security in retirement, their integration with other pension systems, and their role in mitigating risks associated with demographic changes and economic volatility. Through a comprehensive literature review and analysis, the study highlights the benefits and challenges of personal accumulative pensions and provides recommendations for enhancing their effectiveness.

This annotation provides a concise overview of the paper's focus on improving warehouse systems in logistics, summarizing the main methods and benefits discussed.

Iatrogenic (Greek iatrogenic doctor, the gene that occurred) iatrogenic disease, the term has 2 meanings:1. Iatrogenic diseases, diseases that arise in connection with careless statements of doctors or other representatives of medical personnel that affect the psyche of the patient. 2. Pathology of treatment - pathological conditions and diseases caused by diagnostic, prophylactic and therapeutic action.

The Republic of Uzbekistan, a country located in the heart of Central Asia, has been actively pursuing a policy of economic liberalization and integration into the global economy since its independence in 1991. One of the key drivers of this process has been the attraction of foreign investments, which have played a crucial role in the development of the country's foreign economic activity. This article will examine the development of Uzbekistan's foreign economic activity with the help of foreign investments, highlighting the country's achievements, challenges, and prospects for future growth.

Despite the fact that words are practically inexhaustible reserves, their multidimensional and meaningful essence, the diverse nature of their connections, the vocabulary structure of the language consists of a certain system that does not go beyond the general language system, but, on the contrary, actively participates in its logical development

The increasing use of conservation tillage, no-till, and cover crops is changing the way we view the soil and the environment. New concepts and terminology are being used to describe these changes. Understanding the terms defined in this fact sheet will help farmers understand relationships between tillage, crop rotation, cover crops, carbon sequestration, organic matter pool, agricultural sustainability, and soil and water quality.

This study investigates the complex issue of patient refusal as a component of neglect in medical treatment. Patient refusal refers to situations where individuals decline or delay recommended medical care, potentially leading to adverse health outcomes. Through a comprehensive review of literature and case studies, this research explores the underlying factors contributing to patient refusal, including fear, mistrust, cultural beliefs, and autonomy concerns. Additionally, the study examines the legal and ethical implications of patient refusal for healthcare providers, highlighting the delicate balance between respecting patient autonomy and ensuring patient safety. By shedding light on the multifaceted nature of patient refusal, this research aims to inform healthcare practices and policies aimed at mitigating neglect and promoting patient-centered care.

The problem of cervicitis and vulvovaginitis is given special attention all over the world due to the increase in the frequency of their occurrence among women of reproductive age. At present, the significant role of chronic cervicitis in the development of oncological and other diseases of the reproductive system, including cervical cancer, has been proven.  epidemiology of cervicitis. However, it should be emphasized that many researchers unconditionally recognize the need for further study of both etiological factors and pathogenetic mechanisms of the formation of inflammatory cervical disease for the reasonable treatment of patients suffering from this disease

Thin endometrium, defined as an endometrial thickness less than 7 mm in the proliferative phase or less than 8 mm in the secretory phase, is a common finding in women with infertility. While the exact cause of thin endometrium is unknown, it is thought to be related to several factors, including hormonal imbalances, uterine abnormalities, and chronic inflammation. Thin endometrium can interfere with implantation, the process by which a fertilized egg attaches to the uterine lining and begins to develop. As a result, women with thin endometrium may have difficulty becoming pregnant.

This review article will discuss the current understanding of thin endometrium and its impact on infertility. We will review the different causes of thin endometrium, the diagnostic criteria, and the various treatment options available. We will also discuss the evidence supporting the use of different treatment approaches and the factors that may influence treatment success. Finally, we will discuss future directions for research in this area.

On the basis of statistical diagnostic indicators, the spread of tuberculosis among the world's population was studied. The data obtained will help improve the early diagnosis of patients with active tuberculosis and their provision of planned dental care.

Man as a biological species provides its existence due to the creative transformation of the surrounding world, the development of culture and technologies. However, new technologies, being the fruit of human imagination and creativity, in turn, also change a person, complementing and transforming his usual habitat. Since the beginning of the emergence of technogenic civilization the dominant technologies of a particular historical period become the provider of metaphors for era-appropriate understanding person. In modern mechanism, the human body is compared to a machine - Sigmund Freud draws an analogy of what is repressed in psyche with a steam boiler, the lid of which blows off due to steam pressure - and in the twentieth century. Consciousness a person is like a computer. In modern times, one of these metaphors is digital networks with many nodes, while a person is not a network node, but is “distributed” among many of them.

Pregnant women have the highest risk of dental diseases [3]. According to a number of authors, the prevalence of dental caries during the physiological period of pregnancy is 91.4%, in 90% of cases, diseases of the parodont tissue, mainly damage to healthy teeth with an acute course of the carious process, make up 38% of pregnant women. [5]. Secondary caries, development of the caries process, enamel hyperesthesia occur in 79% of pregnant women [11]. At the same time, the growth intensity of dental caries in terms of the absolute increase in the index of caries-fillers-removed teeth during pregnancy is 0.83 [2].

This article is about "The role and importance of empirical research in education", and comments on the theoretical and practical aspects of empirical research in the field of education and ongoing research are given.

In the last decade, mesial occlusion has been studied in many countries through the use of modern diagnostic technologies for the timely treatment of this anomaly. The basis for diagnosis is an X-ray cephalometric examination of the facial skeleton, which allows us to identify the leading pathogenetic mechanisms and conduct differential diagnosis of combined forms of anomaly, which cannot be carried out on the basis of clinical data alone (N.G.Abolmasov, 1982; E.N.Zhulev, 1986, etc.).

: Pregnant women have the highest risk of dental diseases [3]. According to a number of authors, the prevalence of dental caries during the physiological period of pregnancy is 91.4%, in 90% of cases, diseases of the parodont tissue, mainly damage to healthy teeth with an acute course of the carious process, make up 38% of pregnant women. [5]. Secondary caries, development of the caries process, enamel hyperesthesia occur in 79% of pregnant women [11]. At the same time, the growth intensity of dental caries in terms of the absolute increase in the index of caries-fillers-removed teeth during pregnancy is 0.83 [2]

Entrepreneurship has emerged as a crucial driver of economic growth and job creation in Uzbekistan, where the government has set ambitious targets to address unemployment challenges. This paper explores the role of entrepreneurship in tackling unemployment in Uzbekistan, examining government initiatives, policy interventions, and the potential for entrepreneurship to drive economic growth. Drawing on a literature review, the paper analyzes the complex relationship between entrepreneurship and unemployment, highlighting the factors influencing entrepreneurial activity and its impact on job creation. Additionally, the paper presents empirical findings on trends in employment and GDP, shedding light on the economic performance of Uzbekistan over the studied period. The analysis reveals regional variations in small business employment and underscores the importance of tailored policies to support entrepreneurship and address regional disparities effectively. Overall, the paper provides insights into the opportunities and challenges of entrepreneurship in Uzbekistan's quest for sustainable development and inclusive growth.

In the complex treatment of generalized periodontitis, special attention is paid to the correct combination of conservative and surgical methods of treatment, which reduce the activity of destructive processes in periodontal tissues and restore the lost anatomy [1-9]. However, despite various additions and modifications, conservative and surgical interventions on the periodontal itself do not create sufficient conditions for effective relief of pathological processes and restoration of periodontal tissues [10-18]. In some cases, the use of new technologies, including the use of occupational hygiene, dental splints and other conservative methods of treatment, does not lead to the stabilization of destructive processes in the alveolar process, and in some cases contributes to the further destruction of periodontal tissues and surrounding bone tissue with the formation of defects of various sizes. The problem of dental preservation in patients with generalized periodontitis of II-III severity is still relevant. The organizational inconsistency of dentists of different specialties, the lack of a real medical examination of patients with periodontal disease create prerequisites for the interruption of treatment at the level of conservative therapeutic agents and the active course of destruction of bone tissue of alveolar processes.

A number of studies that electronic axiography and digital kinesiography were employed to ascertain the efficacy of various orthopedic manipulations prior to and following treatment. These studies were conducted by V. D. et al. (2014), Persin L. S. et al. (2019), Arutyunov S. D. et al. (2019), and Mamedov Hell (2019). A. et al. (2019), Dubova L.V. et al. (2020), and Lebedenko I. Yu. et al. (2022). There is a paucity of evidence-based approaches to the assessment of prosthetic planning and treatment for partially edentulous patients. This is an area of clinical practice that is of paramount importance. The most crucial of these include the assessment of the efficacy of orthodontic treatment, the evaluation of the occlusal relationship and the degree of its correction, the assessment of the impact of installed orthodontic appliances on the masticatory muscles and the microbiocenosis of the oral cavity, the determination of indications for orthodontic treatment of patients with partial tooth loss, and the formulation of treatment strategies.

Undifferentiated connective tissue dysplasia (UCTD) is a complex and heterogeneous condition that presents with a variety of clinical manifestations affecting multiple organ systems. This review article aims to provide an overview of the clinical manifestations and impact of UCTD on individuals. The diagnostic criteria, pathophysiology, and management strategies for UCTD will also be discussed. Understanding the diverse clinical presentations and potential consequences of UCTD is crucial in improving patient outcomes and guiding appropriate treatment approaches.

Corpus linguistics is the section of computer linguistics which engaged in development of general principles for the construction and use of linguistic corpora using computer technologies. Under the linguistic or language corpus of texts is understood large, machine- readable format, unified, structured, marked, philologically competent array of linguistic data designed to solve specific linguistic problems.

Currently, there is a clear trend towards an increase in the elderly and senile population. Their share in the population in many countries exceeded 20%. Prevention of aging is one of the most actively and dynamically developing new areas of medicine in recent years. In the process of natural aging, factors such as decreased metabolism, dysfunction of the endocrine system and immunity, impaired microcirculation and neurohumoral regulation play a role. The age-related decrease in estrogen levels in a woman's body plays a significant role in the development of endogenous changes in COPD. Skin aging plays an important role in the mechanisms of the general biological aging process of the body. On the one hand, the oral mucosa determines the metabolic, structural and functional changes common to the entire body, and the condition of the skin as a whole may indicate the degree of aging of the body. On the other hand, the oral cavity is an organ that is constantly in contact with the external environment, as a result of which signs of aging may appear much earlier than in other organs.

In this article, the spiritual and moral education of students of higher educational institutions is described as a pedagogical problem, and the concept of spirituality is defined from a philosophical, pedagogical, and psychological point of view. Also, the goals and tasks of spiritual and moral education of students were analyzed from a scientific and pedagogical point of view.

This article provides information on the impact of manipulation in family relationships on a child's personality.

The main task of diagnostics is to identify pathology at the earliest possible stages of its development, before the appearance of severe forms and complications. However, given the low awareness of the population and the long-term chronic course of periodontal diseases, patients with advanced periodontitis at a severe stage seek treatment. In these conditions, individual assessment and prediction of the risk of periodontitis in patients with arterial hypertension is relevant. Such studies will serve as a basis for identifying patients with a high risk of developing periodontal diseases, grouping them for the purpose of dental monitoring and implementing measures to neutralize the negative effects of periodontal diseases on the course of hypertension.

The osteochondrodysplasias or skeletal dysplasias are a heterogenous group of over 350 distinct disorders of skeletogenesis. Many manifest in the prenatal period, making them amenable to ultrasound prenatal diagnosis. A retrospective analysis evaluated 1,500 cases referred to the International Skeletal Dysplasia Registry (ISDR) to determine the relative frequency of specific osteochondrodysplasias and correlation of ultrasound versus radiographic diagnoses for these disorders. Within the retrospective cohort of 1,500 cases, 85% of the referred cases represented well-defined skeletal dysplasias, and the other 15% of cases were a mixture of genetic syndromes and probable early-onset intrauterine growth restriction. The three most common prenatal-onset skeletal dysplasias were osteogenesis imperfecta type 2, thanatophoric dysplasia and achondrogenesis 2, accounting for almost 40% of the cases. In a prospective analysis of 500 cases using a standardized ultrasound approach to the evaluation of these disorders, the relative frequencies of osteogenesis imperfecta type 2, thanatophoric dysplasia and achondrogenesis 2 were similar to the retrospective analysis. This study details the relative frequencies of specific prenatal-onset osteochondrodysplasias, their heterogeneity of prenatal-onset skeletal disorders and provides a standardized prenatal ultrasound approach to these disorders which should aid in the prenatal diagnosis of fetuses suspected of manifesting skeletal dysplasias.

This article discusses the main macroeconomic indicators, why they are important for the country's economy, the interdependence of macroeconomic indicators, gross domestic product, foreign trade turnover, the impact of the increase in the total income of the population on society

This article discusses innovative methods for teaching programming, including the use of virtual reality (VR) and augmented reality (AR) technologies for teaching arrays. The advantages of using interactive and visual methods, which contribute to better understanding and increased student motivation, are described. The article also covers mathematical models, such as linear regression and clustering, used to assess student performance and adapt educational materials. The results show significant improvements in students' understanding of concepts, practical skills, and motivation.

In adults, acute leukemia is diagnosed in 75.0% of cases of hematological diseases, and the survival rate decreases with age. [1]. Patients with acute leukemia due to clinical manifestations of pathology in the oral cavity seek consultation with the dentist, the task of which is to identify oncopathology at an early stage and timely refer the patient to the hematologist for the immediate start of treatment. Much attention has now been paid to studying the effects of medical and social factors on the health of the elderly and the elderly [2-4]. The question of the condition of the teeth in elderly patients suffering from acute leukemia and their impact on the quality of life of these patients has not been adequately studied.

This article discusses various technological innovations in the banking sector that have revolutionized how banks operate and interact with their customers. It covers the introduction of digital banking platforms, the use of blockchain and cryptocurrencies, advancements in artificial intelligence and machine learning, the application of robotic process automation, and the implementation of advanced analytics and big data. Additionally, it touches on the role of regulatory technology (RegTech) in compliance, the growth of contactless payments and mobile wallets, and the integration of biometric security systems. These innovations have significantly enhanced the efficiency, accessibility, and security of financial services, offering a more personalized and streamlined customer experience while ensuring regulatory compliance and operational resilience.

In the ever-evolving landscape of the global economy, the effective management of financial risks has become a critical imperative for businesses engaging in international operations. As companies expand their reach across national borders, they are confronted with a multitude of financial risks that can significantly impact their performance, profitability, and long-term viability. This article delves into the complexities of financial risk management in the context of international business, exploring the various types of risks, strategies for mitigation, and the role of regulatory frameworks in ensuring the stability and resilience of multinational enterprises

This article deals with Factors of innovative approach in improving the pedagogical skills of school teachers. There are some factors about how to be a qualified teacher.