The conditions determining the high prevalence and intensity of major dental diseases against the background of impaired immunological reactivity of organs and tissues of the oral cavity include climatogeographic and social living conditions, the general condition of the body and one of the most common etiological causes threatening both the general health and the oral cavity of the population, - tobacco includes changes in regulatory indicators of immune status caused by smoking Tobacco smoking is an incalculable burden for health authorities and governments in many countries as a socio-economic problem associated with early mortality from smoking-related diseases, disability and economic losses due to absence from the workplace.

inflammatory periodontal diseases, diseases of the oral mucosa, dental caries

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