The social and economic development of a society is largely determined by the level of health of its young population. The objective of this study was to increase the effectiveness of preventive and comprehensive treatment of young patients with major dental diseases using an innovative therapeutic and preventive toothpaste based on organic gel. A group of 32 volunteers participated in the study. All patients underwent a complex dental examination that included basic and additional methods (determination of indices of caries intensity, indicators of oral hygiene (simple hygiene index OHI-S, Silnes-Low index), evaluation of periodontal tissue status (papillary-limbal alveolar abscess index PMA, gingival bleeding in inflammatory periodontal disease index BI Müllmann), evaluation of pain (hypersensitivity) to stimuli using a visual analog scale (VAS), measurement of the electrical conductivity of tooth enamel using the Dentest electrodiagnostic device (ZAO Geosoftident), clinical evaluation of enamel remineralization rate, spectrophotometer "VITA (Easy Shade) (VITA) to evaluate tooth discoloration, oral fluid immunoassay, and cytomorphometric studies of the buccal epithelium. The results of the clinical trials showed that the therapeutic and prophylactic toothpaste has excellent consumer characteristics, has no allergic or local irritant effects on the oral mucosa, improves the natural protection of the oral cavity, effectively cleans up to 100% of the oral cavity, provides anti-inflammatory effects, eliminates gum swelling and bleeding from the first use, reduces tooth sensitivity, reduces tooth enamel structure, and was shown to have no toxic effect on the cells of the buccal epithelium. The results of the clinical trial suggest that the innovative therapeutic and prophylactic dentifrice can be recommended for daily use in a wide range of individuals, as well as in patients with low tooth enamel resistance, various periodontal diseases, and oral mucosa.

Therapeutic and prophylactic dentifrice, clinical study, cytomorphological study

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