Articles
| Open Access |
DOI:
https://doi.org/10.55640/eijmrms-03-07-10
MACRO- AND MICROSCOPIC MORPHOLOGICAL RESULTS OF THE APPLICATION OF XENOTRANSPLANTED SHEEP PERICARDIUM IN TYMPANOPLASTY IN RABBITS WITH CHRONIC OTITIS MEDIA
Botirov A.J. , Researcher Tashkent Medical Academy, UzbekistanAbstract
When an autologous fascia is placed on the drum membrane, at first all kinds of reactive changes develop around it, and in a short period of time a border of demarcation from lympho-histiocytic and monocyto-macrophage cells appears, but these cells do not grow into the fascia, on the contrary, a fibrous membrane appears around it, its surface on the 21st day completely epithelized. When the pericardium of the sheep heart is transplanted into the tympanic membrane for the purpose of closing it, a strong and extensive reactive change develops in response. Necrosis and destruction develop in the xenograft, and a proliferative infiltrate appears around it. Then the xenograft intermingles with the proliferative infiltrate cells that appear around the tissue structures. Young lympho-histiocytic cells turn into fibrocytes and histiocytes, produce fibrous structures and the surface is covered with epithelium.
Keywords
Xenograft,, fibrosis, fascia
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