This article explores how uncertainty is managed and resolved in genomics clinics through the standardization of practices and the reflexive engagement of clinicians with patients. The authors argue that standardization plays a critical role in managing uncertainty in the genomic clinic, but that this standardization must be accompanied by the reflexive engagement of clinicians with patients to ensure that the standardization is appropriate to the unique circumstances of each patient. The article "Reflexive Standardization and the Resolution of Uncertainty in the Genomics Clinic" explores the role of standardization in the practice of genomic medicine. The authors argue that while standardization has been seen as a way to reduce uncertainty in medical practice, in genomics it can also introduce new uncertainties. The article draws on ethnographic research conducted in a genomics clinic, focusing on the practices of standardization and the ways in which clinicians and patients navigate uncertainty. The authors propose the concept of "reflexive standardization" to describe the ways in which standardization can be made more flexible and responsive to the needs of individual patients. They suggest that this approach can help to resolve uncertainties in genomics practice and ensure that patients receive appropriate and personalized care.

Reflexive standardization, genomics clinic, uncertainty

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