Despite the obvious successes in the field of preventive and conservative dentistry, the prevalence of abrasion of teeth (ITP) continues to grow: during the period 1992-2004, the proportion of diseases of hard tissues of teeth with elimination properties increased from 30.9 ± 1.8% to 38.2 ± 1.3%, i.e. increased by 7.3% [1, 7-10]. Many issues related to the diagnosis and planning of an integrated approach to the provision of dental care to patients with moderate CAH have not yet been sufficiently studied and covered [2]. Biologically active calcium phosphate in gel or colloidal state is currently of increasing interest in many areas of clinical medicine related to the problem of regeneration of soft and hard tissues of the body. It has been established that the biological activity of apatite largely depends on the size of its particles or grains, and the higher the dispersion of the substance, the more pronounced it is [3]. The use of pure compounds, as well as various combinations of bioactive substances to improve properties such as adhesion, bioactivity and biocompatibility, is also very promising [4]. A promising direction of modification of calcium hydroxyapatite (HCA) from the point of view of obtaining materials with improved properties is the introduction of fluorine and silicon atoms into the structure of HCA. This transformation increases the stability of the material in the chemically active environment of the human body (due to the presence of fluoride ions) and increases its biological activity (due to the presence of silicate ions), while maintaining the inherent biocompatibility of HAP [5]. Nanotechnology is used in the study, production and use of nanostructures, devices and systems, including targeted control and modification of the shape, size, interaction and integration of their constituent nanoscale elements (1-100 nm) to obtain objects with new chemical, physical and biological properties. A number of technologies and methods. Direct transport of medicines to the focus of the pathological process can increase the effectiveness of existing drug therapies [6]. A promising direction in modern dentistry is the creation of new pharmacological agents with particle sizes of the order of 10-9 (nanoparticles) for noninvasive treatment and early prevention of dental diseases. The aim of the study was to study the effectiveness of new pharmacologically active compositions of nanostructured fluorohydroxyapatite in the treatment of early symptoms of dental hyperextension.

Conservative dentistry, biological activity, bioactivity and biocompatibility

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