The kidneys are paired retroperitoneal organs of the urinary system. Their function is to filter blood and produce urine. Each kidney consists of a cortex, medulla and calyces. The nephron is the main functional unit of the kidney, in charge of removing metabolic waste and excess water from the blood. In this article we will explore the microanatomy of a nephron and learn how their function relates to their histological features.

Kidney,, renal,, suprarenal.

Wolfe F, Smythe HA, Yunus MB, Bennett RM, Bombardier C, Goldenberg DL, Tugwell P, Campbell SM, Abeles M, Clark P, et al: The American College of Rheumatology criteria for the classification of fibromyalgia: report of the multicenter criteria committee. Arthritis Rheum. 1990, 33: 160-172.

Barsky MJ, Borus JF: Functional somatic syndromes. Ann Intern Med. 1999, 130: 910-921.

Gracely RH, Petzke F, Wolf JM, Clauw DJ: Functional magnetic resonance imaging evidence of augmented pain processing in fibromyalgia. Arthritis Rheum. 2002, 46: 1333-1343. 10.1002/art.10225.

Staud R, Vierck CJ, Cannon RL, Mauderli AP, Price DD: Abnormal sensitization and temporal summation of second pain (wind up) in patients with fibromyalgia syndrome. Pain. 2001, 91: 165-175. 10.1016/S0304-3959(00)00432-2.

Buskila D, Neumann L: Genetics of fibromyalgia. Curr Pain Headache Rep. 2005, 9: 313-315.

Buskila D, Neumann L, Press J: Genetic factors in neuromuscular pain. CNS Spectr. 2005, 10: 281-284.

Clauw DJ, Crofford LJ: Chronic widespread pain and fibromyalgia what we know and what we need to know. Best Pract Res Clin Rheumatol. 2003, 17: 685-701. 10.1016/S1521-6942(03)00035-4.